Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23961685 | 0.91 | C3AR1 (0.45) | PTGS1PTGS2C3AR1NOD1CTDSP1 | |
| SCHEMBL22267880 | 0.89 | PTGS1 (0.38) | PTGS1PTGS2C3AR1HTTHPGD | |
| SCHEMBL17722904 | 0.87 | NMT1 (0.45) | PTGS1PTGS2NPY1RNPY2RNPY4R | |
| SCHEMBL21322508 | 0.87 | SIRT5 (0.37) | PTGS1PTGS2ALBC3AR1HTT | |
| SCHEMBL22109548 | 0.86 | C3AR1 (0.39) | ALBC3AR1HPGDALDH1A1MAPT | |
| SCHEMBL19681473 | 0.86 | NPY5R (0.42) | PTGS1PTGS2ALBHTTHPGD | |
| SCHEMBL17722910 | 0.85 | PTGS1 (0.46) | PTGS1PTGS2NPY1RNPY2RNPY4R | |
| SCHEMBL17722906 | 0.85 | NMT1 (0.48) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL18932741 | 0.85 | PTGS1 (0.46) | PTGS1PTGS2NPY1RNPY2RNPY4R | |
| SCHEMBL19257624 | 0.84 | NPY5R (0.38) | PTGS1PTGS2NPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134547-A1 | TUBULYSIN ANALOGS AND METHODS FOR THEIR PREPARATION | PFIZER INC. (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017132173-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |