Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 4/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203573 | 0.87 | PTGS1 (0.40) | C3AR1OPRM1OPRD1OPRK1CTDSP1 | |
| SCHEMBL21322509 | 0.85 | SIRT5 (0.39) | SIRT5C3AR1OPRM1OPRD1OPRK1 | |
| SCHEMBL19203551 | 0.83 | FOLH1 (0.37) | SIRT5ALBSMN1; SMN2 | |
| SCHEMBL22109548 | 0.83 | C3AR1 (0.39) | SIRT5C3AR1CTDSP1MEN1KLK7 | |
| SCHEMBL19203408 | 0.81 | SIRT5 (0.41) | SIRT5C3AR1CTDSP1ALDH1A1HPGD | |
| SCHEMBL18937746 | 0.79 | NPY5R (0.40) | SIRT5C3AR1CTDSP1PTGS1PTGS2 | |
| SCHEMBL17722903 | 0.79 | NPY5R (0.40) | SIRT5C3AR1CTDSP1PTGS1PTGS2 | |
| SCHEMBL17722904 | 0.78 | NMT1 (0.45) | PTGS1PTGS2 | |
| SCHEMBL24860409 | 0.78 | C3AR1 (0.38) | SIRT5C3AR1CTDSP1MEN1KLK7 | |
| SCHEMBL19170696 | 0.78 | SIRT5 (0.35) | SIRT5C3AR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3273998-B1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMA (US) | 2019-09-04 | — | — | EP | disclosed |