Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203573 | 0.86 | PTGS1 (0.40) | C3AR1CTDSP1KMT2AALBKDM4E | |
| SCHEMBL13021070 | 0.83 | RRM1 (0.39) | KMT2AMEN1ALBPOLBRRM1 | |
| SCHEMBL21322508 | 0.83 | SIRT5 (0.37) | C3AR1CTDSP1KMT2AMEN1KLK7 | |
| SCHEMBL17722911 | 0.83 | FURIN (0.35) | C3AR1CTDSP1KMT2AMEN1KLK7 | |
| SCHEMBL18937746 | 0.80 | NPY5R (0.40) | C3AR1CTDSP1POLBSIRT5 | |
| SCHEMBL17722903 | 0.80 | NPY5R (0.40) | C3AR1CTDSP1POLBSIRT5 | |
| SCHEMBL18937738 | 0.80 | SIRT2 (0.40) | SIRT5 | |
| SCHEMBL17722926 | 0.77 | KISS1R (0.38) | C3AR1CTDSP1POLBSIRT5 | |
| SCHEMBL23961685 | 0.76 | C3AR1 (0.45) | C3AR1CTDSP1KMT2AMEN1KLK7 | |
| SCHEMBL17722924 | 0.76 | NPY5R (0.39) | C3AR1CTDSP1KMT2AMEN1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458102-B1 | ANTI-CMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | ABBVIE BIOTHERAPEUTICS INC (US) | 2020-06-17 | — | — | EP | disclosed |