Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461668 | 0.85 | RXFP1 (0.40) | KDM4EALDH1A1CYP1A2RXFP1LMNA | |
| SCHEMBL3461117 | 0.85 | ACHE (0.46) | KDM4EALDH1A1CYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL3460311 | 0.85 | ADRA2A (0.49) | KDM4ECYP1A2CYP2D6L3MBTL1RXFP1 | |
| SCHEMBL3461436 | 0.84 | RXFP1 (0.40) | KDM4EALDH1A1CYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL3461123 | 0.83 | ADRA2A (0.48) | KDM4ECYP1A2CYP2D6L3MBTL1HRH4 | |
| SCHEMBL3460998 | 0.81 | ADRA2A (0.46) | KDM4ECYP1A2CYP2D6L3MBTL1HRH4 | |
| SCHEMBL3462075 | 0.80 | RXFP1 (0.36) | KDM4EALDH1A1CYP1A2RXFP1LMNA | |
| SCHEMBL13640246 | 0.80 | TUBB4A (0.48) | KDM4EALDH1A1CYP1A2RXFP1LMNA | |
| SCHEMBL3462580 | 0.79 | HTT (0.51) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL12852196 | 0.79 | DRD4 (0.36) | KDM4EALDH1A1CYP1A2CYP2D6RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326327-A2 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | SRI International (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010033198-A2 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | SRI INTERNATIONAL (US) | 2010-03-25 | — | — | WO | disclosed |