Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 7/20 | 0.48 |
| ▸ | TUBB | P07437 | 7/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17396502 | 0.81 | MAP2 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1921071 | 0.81 | KDM4E (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1920387 | 0.80 | KDM4E (0.41) | LMNACHUKCYP1A2GAAHPGD | |
| SCHEMBL1920226 | 0.79 | KIF11 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1920490 | 0.79 | AR (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3209389 | 0.77 | KDM4E (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21086289 | 0.77 | GRIN2D (0.49) | LMNACHUKCYP1A2GAAHPGD | |
| SCHEMBL3461668 | 0.76 | RXFP1 (0.40) | LMNACHUKCYP1A2GAAHPGD | |
| SCHEMBL3460311 | 0.76 | ADRA2A (0.49) | CYP1A2GAAKDM4EMAPTRXFP1 | |
| SCHEMBL31612421 | 0.76 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694057-B1 | LIPOXYGENASE INHIBITORS | STANFORD RES INST INT (US) | 2019-06-05 | — | — | EP | disclosed |
| US-8399502-B2 | Analogs of indole-3-carbinol and their use as agents against infection | SRI INTERNATIONAL (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120283240-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | SRI INTERNATIONAL | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283240-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | IDO1, IDO2, TDO2 | TUBB4A 1702/4885TUBB 632/4885TUBA3C 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.