Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.45 |
| ▸ | CPT2 | P23786 | 1/20 | 0.44 |
| ▸ | CPT1A | P50416 | 1/20 | 0.44 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634134 | 0.93 | DNM1 (0.54) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL31318140 | 0.87 | PLA2G2C (0.77) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL31364557 | 0.87 | PLA2G2C (0.77) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL2482500 | 0.87 | PLA2G2C (0.77) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL27753924 | 0.87 | PLA2G2C (0.77) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL25067268 | 0.87 | PLA2G2C (0.77) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL6943359 | 0.87 | PLA2G2C (0.67) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL30679514 | 0.87 | PLA2G2C (0.77) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL27536177 | 0.87 | PLA2G2C (0.77) | PLA2G2CDNM1PLA2G10MEN1KMT2A | |
| SCHEMBL11638748 | 0.86 | FAAH (0.51) | PLA2G2CDNM1PLA2G10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10415040-B2 | Nucleic acid amphiphiles and nanostructures | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-09-17 | — | — | US | disclosed |
| US-20170218367-A1 | NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10415040-B2 | Nucleic acid amphiphiles and nanostructures | EWSR1, ANXA4, POLRMT | PLA2G2C 3329/4885DNM1 152/4885PLA2G10 3061/4885 |
| US-20170218367-A1 | NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES | EWSR1, ANXA4, POLRMT | PLA2G2C 3329/4885DNM1 152/4885PLA2G10 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.