SCHEMBL19204522

SCHEMBL19204522

C=C/C=C\c1c(C)oc2c(-c3ccccc3)cccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 3/20 0.37
PIK3CA P42336 3/20 0.37
PIK3CB P42338 3/20 0.37
PIK3CG P48736 3/20 0.37
PRKDC P78527 8/20 0.36
ALDH1A1 P00352 5/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
KDM4E B2RXH2 2/20 0.34
BRD4 O60885 2/20 0.34
BRD2 P25440 2/20 0.34
BRD3 Q15059 2/20 0.34
TSHR P16473 2/20 0.34
CYP1A2 P05177 2/20 0.34
PDE2A O00408 1/20 0.34
PIK3C2A O00443 1/20 0.34
PIK3R2 O00459 1/20 0.34
PIK3C2B O00750 1/20 0.34
PDE5A O76074 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23652448 0.92 PRKDC (0.40) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL24026941 0.88 TDP1 (0.42) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL22429327 0.84 ALOX5 (0.40) PIK3CDPIK3CBPRKDCNPC1MEN1
SCHEMBL24275367 0.84 ALDH1A1 (0.39) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL23521728 0.83 ALDH1A1 (0.40) PIK3CAALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL22432380 0.80 MCL1 (0.38) PRKDCALDH1A1CYP1A2
SCHEMBL21765402 0.78 ELANE (0.33) PIK3CAALDH1A1TSHRCYP3A4HSD17B10
SCHEMBL10068830 0.78 LOXL2 (0.33)
SCHEMBL23542904 0.77 CYP1A2 (0.36) PRKDCALDH1A1SMN1; SMN2KDM4ETSHR
SCHEMBL26311586 0.75 PRKDC (0.33) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210384440-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-12-09 US disclosed
US-20170222156-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210384440-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SUN2, ARNT, AHR PIK3CD 4698/4885PIK3CA 4577/4885PIK3CB 4713/4885
US-20170222156-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SUN2, ARNT, AHR PIK3CD 4698/4885PIK3CA 4577/4885PIK3CB 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.