SCHEMBL19204523

SCHEMBL19204523

Cc1cccc(-c2cc3ccccc3c3c2sc2c(-c4ccccc4)cccc23)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 1/20 0.40
S1PR5 Q9H228 1/20 0.40
ENPP1 P22413 1/20 0.40
LIMK1 P53667 1/20 0.39
MAOB P27338 3/20 0.38
ADORA1 P30542 3/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MCL1 Q07820 2/20 0.37
BAD Q92934 1/20 0.37
KMT2A Q03164 2/20 0.36
NR1I3 Q14994 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21335448 1.00 S1PR4 (0.40) S1PR4S1PR5ENPP1LIMK1MAOB
SCHEMBL18267882 0.85 LIMK1 (0.47) S1PR4S1PR5ENPP1LIMK1ADORA1
SCHEMBL21157800 0.85 ALDH1A1 (0.40) S1PR4S1PR5LIMK1ALDH1A1HPGD
SCHEMBL23348348 0.83 LIMK1 (0.43) LIMK1ADORA1ALDH1A1HPGDTSHR
SCHEMBL23348346 0.83 ADORA3 (0.42) MAOBADORA1ALDH1A1HPGDTSHR
SCHEMBL18416260 0.83 ALOX5 (0.47) S1PR4S1PR5ENPP1LIMK1ADORA1
SCHEMBL21157803 0.82 CYP1A2 (0.34) S1PR4S1PR5LIMK1MAOBADORA1
SCHEMBL20064201 0.82 LIMK1 (0.40) S1PR4S1PR5LIMK1ADORA1ALDH1A1
SCHEMBL21157053 0.81 LIMK1 (0.39) S1PR4S1PR5LIMK1ADORA1ALDH1A1
SCHEMBL23989066 0.80 MAOB (0.45) S1PR4S1PR5ENPP1LIMK1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210384440-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-12-09 US disclosed
US-10411193-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-09-10 US disclosed
US-20170222156-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210384440-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SUN2, ARNT, AHR S1PR4 4580/4885S1PR5 4657/4885ENPP1 2988/4885
US-10411193-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SUN2, ARNT, AHR S1PR4 4580/4885S1PR5 4657/4885ENPP1 2988/4885
US-20170222156-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SUN2, ARNT, AHR S1PR4 4580/4885S1PR5 4657/4885ENPP1 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.