Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | FOXM1 | Q08050 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320640 | 0.84 | ALDH1A1 (0.32) | MGLL | |
| SCHEMBL25910791 | 0.84 | ALDH1A1 (0.32) | MGLL | |
| SCHEMBL30519034 | 0.84 | ALDH1A1 (0.32) | MGLL | |
| SCHEMBL25320643 | 0.84 | ALDH1A1 (0.32) | MGLL | |
| SCHEMBL25911592 | 0.83 | MGLL (0.30) | MGLL | |
| SCHEMBL29030456 | 0.83 | ESR1 (0.38) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL10199696 | 0.83 | ESR1 (0.38) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL29030455 | 0.83 | ESR1 (0.38) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7524110 | 0.83 | RECQL (0.43) | ESR1 | |
| SCHEMBL25519028 | 0.79 | ESR1 (0.40) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410064-A | Method for synthesizing 2- (alpha-methoxy-3-hydroxy benzylidene) adamantane compound | 西安交通大学 | 2023-07-11 | — | — | CN | disclosed |
| US-20220047725-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-02-17 | — | — | US | disclosed |
| US-11179482-B2 | Chemiluminescent probes for diagnostics and in vivo imaging | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2021-11-23 | — | — | US | disclosed |
| EP-3408349-B1 | CHEMILUMINESCENT FLUOROPHOR-LINKED ADAMANTYLENE-DIOXETANE PROBES AS DIAGNOSTICS OR IN-VIVO IMAGING SENSORS | UNIV RAMOT (IL) | 2021-03-31 | — | — | EP | disclosed |
| US-20200237932-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2020-07-30 | — | — | US | disclosed |
| US-10660974-B2 | Chemiluminescent probes for diagnostics and in vivo imaging | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2020-05-26 | — | — | US | disclosed |
| US-20190290787-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-09-26 | — | — | US | disclosed |
| WO-2017130191-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660974-B2 | Chemiluminescent probes for diagnostics and in vivo imaging | DAXX, DCAF15, DCAF1 | ESR1 282/4885CA12 293/4885CA1 1716/4885 |
| US-20200237932-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | DAXX, DCAF15, CDY1; CDY1B | ESR1 448/4885CA12 59/4885CA1 504/4885 |
| US-20220047725-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | DAXX, DCAF15, CDY1; CDY1B | ESR1 448/4885CA12 59/4885CA1 504/4885 |
| US-11179482-B2 | Chemiluminescent probes for diagnostics and in vivo imaging | DAXX, DCAF15, CDY1; CDY1B | ESR1 448/4885CA12 59/4885CA1 504/4885 |
| US-20190290787-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | DAXX, DCAF15, DCAF1 | ESR1 282/4885CA12 293/4885CA1 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.