Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.41 |
| ▸ | TUBB | P07437 | 5/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030455 | 0.83 | ESR1 (0.38) | ESR1 | |
| SCHEMBL29030456 | 0.83 | ESR1 (0.38) | PDE4DESR1P4HB | |
| SCHEMBL10199696 | 0.83 | ESR1 (0.38) | ESR1ALDH1A1 | |
| SCHEMBL19204564 | 0.83 | ESR1 (0.38) | ESR1 | |
| SCHEMBL10199844 | 0.82 | PKM (0.39) | PDE4DPDE4BPDE4APDE4CPKM | |
| SCHEMBL25519028 | 0.79 | ESR1 (0.40) | ESR1 | |
| SCHEMBL8854606 | 0.79 | ESR1 (0.52) | ESR1 | |
| SCHEMBL8749248 | 0.78 | KDM2B (0.41) | TUBB3PKMCNR2ESR1ALDH1A1 | |
| SCHEMBL7523187 | 0.77 | PKM (0.39) | PDE4DPDE4BPDE4APDE4CPKM | |
| SCHEMBL14514173 | 0.77 | CNR2 (0.47) | CNR2ESR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666891-B1 | CHEMILUMINESCENT ELECTRON-RICH ARYL-SUBSTITUTED 1,2-DIOXETANES | ABBOTT LAB (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6139781-A | SUBSTITUTED ARYL-CONTAINING 1,2-DIOXETANE COMPOUNDS CAN BE USED AS DIRECT LABELS IN AN IMMUNOASSAY OR WHEN DERIVATIZED WITH AN APPROPRIATE LEAVING GROUP, CAN BE USED AS SUBSTRATE FOR AN ENZYME IMMUNOASSAY | ABBOTT LABORATORIES (US) | 2000-10-31 | — | — | US | disclosed |
| US-6001561-A | AN ANALYTE-SPECIFIC BINDING MEMBER CONJUGATED TO A CHEMILUMINESCENT COMPOUND; FOR SENSITIVE AND ACCURATE ANALYSIS AND FOR CONTROLLING TIMING OF LUMINESCENT REACTION | ABBOTT LABORATORIES (US) | 1999-12-14 | — | — | US | disclosed |
| US-6001659-A | DETERMINING PRESENCE OF ANALYTE IN SAMPLE BY CONTACTING WITH INDICATOR OF AN ANALYTE-SPECIFIC BINDING MEMBER CONJUGATED TO A CHEMILUMINESCENT COMPOUND, AND DETECTING SIGNAL GENERATED; TIMING OF LUMINESCENT REACTION CAN BE CONTROLLED | ABBOTT LABORATORIES (US) | 1999-12-14 | — | — | US | disclosed |
| US-5780249-A | SENSITIVE AND ACCURATE RECEPTOR BINDING ASSAY, IMMUNOASSAY | ABBOTT LABORATORIES (US) | 1998-07-14 | — | — | US | disclosed |
| US-5607625-A | TEST KITS CONTAINING THE DIOXETANES | ABBOTT LABORATORIES (US) | 1997-03-04 | — | — | US | disclosed |
| US-5603868-A | USEFUL FOR IMMUNOASSAY | ABBOTT LABORATORIES (US) | 1997-02-18 | — | — | US | disclosed |