Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 3/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 7/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31539789 | 0.88 | CYP4F2 (0.46) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL19204859 | 0.86 | CYP4F2 (0.47) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL767235 | 0.85 | CYP4F2 (0.44) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL30162853 | 0.85 | LMNA (0.48) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL25073931 | 0.82 | CYP4F2 (0.42) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL806349 | 0.81 | RXRA (0.43) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL29218312 | 0.81 | EGFR (0.45) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL30162823 | 0.81 | EGFR (0.45) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL30950246 | 0.81 | CYP4F2 (0.45) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL21196196 | 0.81 | CYP4F2 (0.45) | CYP4F2CYP4A11LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |