Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920311 | 0.95 | CRHBP (0.34) | UTS2RUSP2LMNAOXTRAVPR1A | |
| SCHEMBL1920802 | 0.88 | LMNA (0.39) | UTS2RUSP2LMNAOXTRCRHBP | |
| SCHEMBL1921417 | 0.87 | DPP4 (0.37) | UTS2RLMNACRHBPCRHR2HCRTR2 | |
| SCHEMBL1629351 | 0.87 | LMNA (0.47) | UTS2RUSP2LMNAOXTRAVPR1A | |
| SCHEMBL1920213 | 0.84 | KMT2A (0.41) | UTS2RUSP2LMNAOXTRAVPR1A | |
| SCHEMBL1921724 | 0.83 | UTS2R (0.38) | UTS2ROXTRCRHBPCRHR2HCRTR2 | |
| SCHEMBL1629605 | 0.83 | UTS2R (0.47) | UTS2ROXTRAVPR1ACRHBPCRHR2 | |
| SCHEMBL1920502 | 0.81 | LMNA (0.41) | UTS2RUSP2LMNACRHBPCRHR2 | |
| SCHEMBL1920310 | 0.81 | CRHBP (0.40) | LMNAOXTRAVPR1ACRHBPCRHR2 | |
| SCHEMBL1630051 | 0.80 | HCRTR2 (0.44) | USP2LMNAOXTRAVPR1ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245006-B1 | SULFONAMIDES AS OREXIN ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2011-06-01 | — | — | EP | disclosed |