Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297850 | 0.89 | PYCR1 (0.55) | APLNRIDO1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL12049800 | 0.81 | APLNR (0.59) | APLNRIDO1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL5270803 | 0.81 | APLNR (0.59) | APLNRIDO1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL22695349 | 0.79 | PYCR1 (0.50) | APLNRIDO1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL385286 | 0.79 | HRH3 (0.58) | APLNRIDO1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL4611890 | 0.79 | PYCR1 (0.69) | APLNRIDO1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7345643 | 0.77 | AOC3 (0.58) | APLNRIDO1ALDH1A1SMN1; SMN2PYCR1 | |
| SCHEMBL7047446 | 0.77 | APLNR (0.55) | APLNRIDO1ALDH1A1SMN1; SMN2PYCR1 | |
| SCHEMBL17099352 | 0.77 | APLNR (0.55) | APLNRIDO1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL11172244 | 0.77 | PYCR1 (0.61) | APLNRIDO1ALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |