Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.58 |
| ▸ | APLNR | P35414 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | AGXT | P21549 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5314700 | 0.90 | LTA4H (0.60) | AOC3IDO1AGXTHTTLTA4H | |
| SCHEMBL3436401 | 0.90 | AOC3 (0.68) | AOC3APLNRIDO1AGXTTAAR1 | |
| Oxalic Acid SCHEMBL8497670 | 0.89 | ALDH1A1 (0.53) | AOC3APLNRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18553360 | 0.86 | TAAR1 (0.55) | AOC3APLNRIDO1AGXTTAAR1 | |
| SCHEMBL10049173 | 0.84 | AOC3 (0.66) | AOC3APLNRIDO1AGXTTAAR1 | |
| SCHEMBL14492589 | 0.83 | IDO1 (0.54) | AOC3APLNRIDO1AGXTTAAR1 | |
| SCHEMBL12049800 | 0.81 | APLNR (0.59) | AOC3APLNRIDO1AGXTTAAR1 | |
| SCHEMBL5270803 | 0.81 | APLNR (0.59) | AOC3APLNRIDO1AGXTTAAR1 | |
| SCHEMBL385286 | 0.79 | HRH3 (0.58) | AOC3APLNRIDO1AGXTTAAR1 | |
| SCHEMBL4611890 | 0.79 | PYCR1 (0.69) | AOC3APLNRIDO1AGXTPYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |
| US-4358599-A | Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro analogs | A. H. ROBINS COMPANY, INC. (US) | 1982-11-09 | — | — | US | disclosed |
| US-4309552-A | Synthesis of 4-nitro-1,2-hydrocarbyl pyrazolidines and process for preparation thereof | A. H. ROBINS COMPANY, INC. (US) | 1982-01-05 | — | — | US | disclosed |