SCHEMBL7047446

SCHEMBL7047446

COc1ccc(CN(O)Cc2ccc(OC)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.55
ALDH1A1 P00352 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
IDO1 P14902 2/20 0.52
PYCR1 P32322 1/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ACHE P22303 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ALOX5 P09917 1/20 0.49
CALM1 P0DP23 1/20 0.48
CMA1 P23946 1/20 0.48
AGXT P21549 1/20 0.48
LTA4H P09960 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27995373 0.84 ALDH1A1 (0.56) APLNRALDH1A1HTTSMN1; SMN2IDO1
SCHEMBL5270803 0.81 APLNR (0.59) APLNRALDH1A1HTTSMN1; SMN2IDO1
SCHEMBL12049800 0.81 APLNR (0.59) APLNRALDH1A1HTTSMN1; SMN2IDO1
SCHEMBL6233097 0.80 APLNR (0.53) APLNRALDH1A1HTTSMN1; SMN2IDO1
SCHEMBL3722809 0.79 ALDH1A1 (0.56) APLNRALDH1A1HTTSMN1; SMN2ACHE
SCHEMBL4611890 0.79 PYCR1 (0.69) APLNRALDH1A1HTTSMN1; SMN2IDO1
SCHEMBL385286 0.79 HRH3 (0.58) APLNRALDH1A1HTTSMN1; SMN2IDO1
SCHEMBL10614647 0.78 NQO1 (0.58) ALDH1A1SMN1; SMN2KMT2ALTA4H
SCHEMBL19302284 0.78 PYCR1 (0.53) APLNRALDH1A1HTTSMN1; SMN2IDO1
SCHEMBL11437372 0.78 ALDH1A1 (0.49) APLNRALDH1A1HTTSMN1; SMN2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941866-B1 Thermally imageable element having improved room light stability DU PONT (US) 2003-04-16 EP claimed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP claimed
EP-0263068-A1 Compositions stabilized with substituted benzylhydroxylamines CIBA-GEIGY AG (CH) 1988-04-06 EP claimed
US-4717748-A STABILIZING AGAINST OXIDATIVE, THERMAL AND ACTINIC DEGRADATION; USED WITH PHENOLIC ANTIOXIDANTS CIBA-GEIGY CORPORATION (US) 1988-01-05 US claimed
EP-0941866-B1 Thermally imageable element having improved room light stability DU PONT (US) 2003-04-16 EP disclosed
US-6251571-B1 MIXTURE OF OXIDIZER, DYE AND HYDROXYLAMINE E. I. DU PONT DE NEMOURS AND COMPANY 2001-06-26 US disclosed
US-6022873-A Metalloproteinase inhibitors BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-02-08 US disclosed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP disclosed
EP-0263068-A1 Compositions stabilized with substituted benzylhydroxylamines CIBA-GEIGY AG (CH) 1988-04-06 EP disclosed
US-4717748-A STABILIZING AGAINST OXIDATIVE, THERMAL AND ACTINIC DEGRADATION; USED WITH PHENOLIC ANTIOXIDANTS CIBA-GEIGY CORPORATION (US) 1988-01-05 US disclosed