SCHEMBL19205985

SCHEMBL19205985

COc1cccc2cc(C(=O)Cl)ccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
HPGD P15428 2/20 0.53
KDM4E B2RXH2 1/20 0.53
HSD17B10 Q99714 1/20 0.53
KDM2B Q8NHM5 3/20 0.47
FLT3 P36888 1/20 0.43
HPGDS O60760 1/20 0.43
MAPT P10636 3/20 0.42
PTPN1 P18031 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NQO1 P15559 1/20 0.42
HTT P42858 1/20 0.42
LMNA P02545 1/20 0.41
RECQL P46063 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11815168 0.87 ALDH1A1 (0.55) ALDH1A1HPGDKDM4EHSD17B10KDM2B
SCHEMBL10282867 0.85 ALDH1A1 (0.60) ALDH1A1HPGDKDM4EHSD17B10KDM2B
SCHEMBL1144405 0.85 KDM4E (0.62) ALDH1A1HPGDKDM4EHSD17B10KDM2B
SCHEMBL28858601 0.84 LCK (0.56) ALDH1A1HPGDKDM4EHSD17B10KDM2B
SCHEMBL9860196 0.81 SMN1; SMN2 (0.50) ALDH1A1HPGDKDM4EHSD17B10KDM2B
SCHEMBL4145846 0.81 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EHSD17B10KDM2B
SCHEMBL23909525 0.78 PTPN1 (0.51) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL30362287 0.78 PTPN1 (0.51) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL29352187 0.77 KDM4E (0.74) ALDH1A1HPGDKDM4EHSD17B10FLT3
SCHEMBL18941416 0.77 KDM4E (0.74) ALDH1A1HPGDKDM4EHSD17B10FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3216783-B1 SULFONATE COMPOUND, PHOTOACID GENERATOR, AND PHOTOLITHOGRAPHIC RESIN COMPOSITION SAN APRO LTD (JP) 2021-06-09 EP disclosed
CN-106795107-B Sulfonate compound, photoacid generator, and resin composition for lithography 三亚普罗股份有限公司 2021-05-28 CN disclosed
US-10450266-B2 Sulfonate compound, photoacid generator, and resin composition for photolithography SAN-APRO LIMITED (JP) 2019-10-22 US disclosed
EP-3216783-A1 SULFONATE COMPOUND, PHOTOACID GENERATOR, AND PHOTOLITHOGRAPHIC RESIN COMPOSITION San-Apro Ltd. (JP) 2017-09-13 EP disclosed
US-20170233336-A1 SULFONATE COMPOUND, PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY SAN-APRO LIMITED (JP) 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233336-A1 SULFONATE COMPOUND, PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY ASIC1, ASIC3, SULT1A1 ALDH1A1 242/4885HPGD 2260/4885KDM4E 2900/4885
US-10450266-B2 Sulfonate compound, photoacid generator, and resin composition for photolithography ASIC1, ASIC3, SULT1A1 ALDH1A1 242/4885HPGD 2260/4885KDM4E 2900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.