Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932889 | 0.90 | ALDH1A1 (0.44) | PTGS2KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6775469 | 0.87 | GAA (0.45) | PTGS2KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7046945 | 0.84 | PTGS2 (0.57) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL499116 | 0.82 | GAA (0.61) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL4965033 | 0.82 | PTGS2 (0.55) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL2307800 | 0.82 | PTGS2 (0.55) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL2979188 | 0.81 | KMT2A (0.57) | PTGS2HTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL4240508 | 0.81 | PTGS2 (0.53) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4002124 | 0.81 | GAA (0.59) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL2272890 | 0.81 | PTGS2 (0.53) | PTGS2KDM4EHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4406957-B1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LTD (IE) | 2026-04-08 | — | — | EP | disclosed |
| US-12577256-B2 | Aryl receptor modulators and methods of making and using the same | NOGRA PHARMA LIMITED (IE) | 2026-03-17 | — | — | US | disclosed |
| US-20250066384-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2025-02-27 | — | — | US | disclosed |
| EP-4406957-A2 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | Nogra Pharma Limited (IE) | 2024-07-31 | — | — | EP | disclosed |
| US-12012418-B2 | Aryl receptor modulators and methods of making and using the same | NOGRA PHARMA LIMITED (IE) | 2024-06-18 | — | — | US | disclosed |
| EP-3160964-B1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LTD (IE) | 2024-03-13 | — | — | EP | disclosed |
| CN-116947880-A | Aryl receptor modulators and methods of making and using the same | 诺格拉制药有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-111978319-B | Aryl receptor modulators and methods of making and using the same | 诺格拉制药有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-20230234963-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2023-07-27 | — | — | US | disclosed |
| US-20230234963-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2023-07-27 | — | — | US | disclosed |
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994017040-A1 | DIARYLALKYL PIPERIDINES USEFUL AS MULTI-DRUG RESISTANT TUMOR AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| EP-0167204-B1 | METHOD FOR IMPROVING THE ABSORPTION AND EFFECTIVENESS OF A CATECHOLAMINE COMPOUND | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1989-09-27 | — | — | EP | disclosed |
| US-4851526-A | ANTIARRYTHMIA, HYPOTENSIVE, ANTIISCHEMIC | SCHERING A.G. (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0306440-A2 | 1-(4-substituted phenyl)-1H-imidazoles as cardiovascular agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | disclosed |
| US-4673671-A | CONVERSION TO MONO O-PHOSPHATE ESTER | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1987-06-16 | — | — | US | disclosed |
| EP-0167204-A1 | Method for improving the absorption and effectiveness of a catecholamine compound | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1986-01-08 | — | — | EP | disclosed |
| US-4139620-A | HYPOTENSIVE AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4096331-A | HYPOTENSIVE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-06-20 | — | — | US | disclosed |
| US-4013666-A | (8α,13Aβ)-8-CARBOCYCLIC/CARBOCYCLIC METHYL-5,8,13,13A-TETRAHYDRO-2,3,10,11-TETRAMETHOXY-6H-dibenzo[a,g]quinolizines and intermediates thereto | G. D. SEARLE & CO. (US) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577256-B2 | Aryl receptor modulators and methods of making and using the same | AHR, IL23R, ARNT | PTGS2 391/4885KDM4E 2605/4885HTR2A 202/4885 |
| US-20250066384-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | AHR, IFNAR1, IL23R | PTGS2 524/4885KDM4E 3114/4885HTR2A 211/4885 |
| US-12012418-B2 | Aryl receptor modulators and methods of making and using the same | AHR, IL23R, IL2RA | PTGS2 286/4885KDM4E 2908/4885HTR2A 127/4885 |
| US-20230234963-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | AHR, IL23R, IL2RA | PTGS2 286/4885KDM4E 2908/4885HTR2A 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.