Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411180 | 0.90 | PTGS2 (0.57) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL8772755 | 0.90 | PTGS2 (0.52) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL8931216 | 0.87 | PTGS2 (0.48) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL4965033 | 0.86 | PTGS2 (0.55) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL2307800 | 0.86 | PTGS2 (0.55) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL499116 | 0.86 | GAA (0.61) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL7774569 | 0.86 | PTGS2 (0.47) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL8160430 | 0.85 | TUBB1 (0.68) | ALDH1A1GAA | |
| SCHEMBL4240508 | 0.84 | PTGS2 (0.53) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL2272890 | 0.84 | PTGS2 (0.53) | PTGS2KDM4EHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230935-A | Anti-tumor effect and application of compound containing alicyclic structure | LIAONING LIFENG TECHNOLOGY DEV CO LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-102241678-B | Anti-tumor effect and application of alicyclic structure-containing compound | LIAONING LIFENG SCIENTIFIC & TECHNOLOGY DEVELOPMENT Co.,Ltd. (CN) | 2014-10-29 | — | — | CN | disclosed |
| CN-101367749-B | A set of mesidino mesitoyl derivant, preparation and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-04-24 | — | — | CN | disclosed |
| CN-102241678-A | Anti-tumor effect and application of alicyclic structure-containing compound | LIAONING LIFENG TECHNOLOGY DEV CO LTD | 2011-11-16 | — | — | CN | disclosed |
| CN-101367749-A | A set of mesidino mesitoyl derivant, preparation and application thereof | MEDICINE AND BIOENGINEERING IN (CN) | 2009-02-18 | — | — | CN | disclosed |
| US-20030139477-A1 | Polyhydroxylated benzene-containing compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-07-24 | — | — | US | disclosed |
| US-4845129-A | ANTICOAGULANT | SANDOZ PHARM. CORP. (US) | 1989-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139477-A1 | Polyhydroxylated benzene-containing compounds | LIPE, PNLIP, SHBG | PTGS2 1440/4885KDM4E 1521/4885HTR2A 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.