SCHEMBL19207331

SCHEMBL19207331

O=C(O)CCc1ccc(S(=O)(=O)F)cc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68
ALDH1A1 P00352 4/20 0.58
F2 P00734 2/20 0.58
TMPRSS4 Q9NRS4 2/20 0.58
TP53 P04637 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
TSHR P16473 1/20 0.58
NPSR1 Q6W5P4 1/20 0.57
FFAR1 O14842 7/20 0.57
MAPT P10636 1/20 0.55
KEAP1 Q14145 1/20 0.55
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
IDO1 P14902 1/20 0.50
FFAR4 Q5NUL3 1/20 0.49
CYP26B1 Q9NR63 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9845455 0.82 CA1 (0.70) CA1CA2ALDH1A1TSHRNPSR1
SCHEMBL69746 0.81 FFAR1 (0.81) CA1CA2FFAR1KEAP1LMNA
SCHEMBL4964212 0.81 CA2 (1.00) CA1CA2ALDH1A1TSHRNPSR1
SCHEMBL40250 0.81 CA1 (0.68) CA1CA2ALDH1A1NPSR1FFAR1
SCHEMBL1429021 0.81 CA1 (0.68) CA1CA2ALDH1A1NPSR1FFAR1
Lithium Ion SCHEMBL28445902 0.81 CA1 (0.68) CA1CA2ALDH1A1NPSR1FFAR1
SCHEMBL6704542 0.80 CA2 (0.54) CA1CA2ALDH1A1F2TMPRSS4
SCHEMBL14744565 0.79 ALDH1A1 (0.66) CA1CA2ALDH1A1NPSR1FFAR1
Hydrochloric Acid SCHEMBL25264643 0.79 FFAR1 (0.77) CA1CA2FFAR1KEAP1LMNA
SCHEMBL25492504 0.78 CA1 (0.64) CA1CA2ALDH1A1NPSR1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775367-A Nectin-4 targeted bicyclic peptide nuclide ligand, probe, and preparation methods and applications thereof 原子高科股份有限公司 2025-04-08 CN claimed
CN-119775367-A Nectin-4 targeted bicyclic peptide nuclide ligand, probe, and preparation methods and applications thereof 原子高科股份有限公司 2025-04-08 CN disclosed
CN-115721729-A Compounds and methods for treating RNA mediated diseases 阿拉基斯医疗公司 2023-03-03 CN disclosed
US-20220402883-A1 COMPOUNDS AND METHODS FOR MODULATING RNA FUNCTION ARRAKIS THERAPEUTICS, INC. 2022-12-22 US disclosed
US-20220402883-A1 COMPOUNDS AND METHODS FOR MODULATING RNA FUNCTION ARRAKIS THERAPEUTICS, INC. 2022-12-22 US disclosed
CN-108778345-B Compounds and methods for treating RNA-mediated diseases 阿拉基斯医疗公司 2022-11-29 CN disclosed
US-20220281860-A1 COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES ARRAKIS THERAPEUTICS, INC. 2022-09-08 US disclosed
US-20220281860-A1 COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES ARRAKIS THERAPEUTICS, INC. 2022-09-08 US disclosed
US-20200115372-A1 COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES ARRAKIS THERAPEUTICS, INC. 2020-04-16 US disclosed
EP-3478842-A2 COMPOUNDS AND METHODS FOR MODULATING RNA FUNCTION Arrakis Therapeutics, Inc. (US) 2019-05-08 EP disclosed
CN-109563515-A Compound and the method for adjusting RNA function 阿拉基斯医疗公司 2019-04-02 CN disclosed
EP-3411080-A2 COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES Arrakis Therapeutics, Inc. (US) 2018-12-12 EP disclosed
CN-108778345-A Compounds and methods for treating RNA-mediated diseases 阿拉基斯医疗公司 2018-11-09 CN disclosed
WO-2018006074-A2 COMPOUNDS AND METHODS FOR MODULATING RNA FUNCTION ARRAKIS THERAPEUTICS, INC. (US) 2018-01-04 WO disclosed
WO-2017136450-A2 COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES ARRAKIS THERAPEUTICS, INC. (US) 2017-08-10 WO disclosed
WO-2017136450-A2 COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES ARRAKIS THERAPEUTICS, INC. (US) 2017-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281860-A1 COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES NSUN3, NSUN2, POLRMT CA1 4668/4885CA2 4711/4885ALDH1A1 2596/4885
US-20200115372-A1 COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES NSUN3, NSUN2, POLRMT CA1 4668/4885CA2 4711/4885ALDH1A1 2596/4885
US-20220402883-A1 COMPOUNDS AND METHODS FOR MODULATING RNA FUNCTION NSUN3, NSUN2, METTL16 CA1 4671/4885CA2 4692/4885ALDH1A1 3659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.