Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796348 | 0.86 | DPP4 (0.31) | — | |
| SCHEMBL1136761 | 0.79 | LMNA (0.32) | EPHX2 | |
| SCHEMBL6632333 | 0.79 | GPR119 (0.33) | GPR119EPHX2 | |
| SCHEMBL6632336 | 0.79 | HTT (0.36) | GPR119EPHX2HTTCA12CA2 | |
| SCHEMBL6069611 | 0.79 | GNAI3 (0.33) | — | |
| SCHEMBL4615811 | 0.79 | — | — | |
| SCHEMBL22991203 | 0.74 | L3MBTL1 (0.34) | GPR119EPHX2HTTCA12CA2 | |
| SCHEMBL27644443 | 0.74 | CYP2D6 (0.46) | — | |
| SCHEMBL477228 | 0.74 | — | — | |
| SCHEMBL1801925 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134685-A2 | NOVEL HYDRAZINO COMPOUNDS AS BTK INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |