Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | AMD1 | P17707 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TEC | P42680 | 1/20 | 0.36 |
| ▸ | TXK | P42681 | 1/20 | 0.36 |
| ▸ | BLK | P51451 | 1/20 | 0.36 |
| ▸ | BMX | P51813 | 1/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20480733 | 0.93 | BTK (0.42) | TLR7EEF2KJAK2JAK3JAK1 | |
| SCHEMBL16143478 | 0.93 | BTK (0.42) | TLR7EEF2KJAK2JAK3JAK1 | |
| SCHEMBL15156546 | 0.86 | EGFR (0.44) | JAK2JAK3JAK1BTKLCK | |
| SCHEMBL23803929 | 0.84 | ADORA3 (0.49) | TLR7EEF2KPIK3CDPIK3CAPIK3CG | |
| SCHEMBL28881338 | 0.83 | SRC (0.50) | PIK3CDEGFRSRC | |
| SCHEMBL25269666 | 0.81 | MTOR (0.44) | TLR7JAK2JAK3JAK1PIK3CD | |
| SCHEMBL30563726 | 0.80 | TLR7 (0.44) | TLR7EEF2KAMD1NSD2NSD3 | |
| SCHEMBL18618395 | 0.80 | BTK (0.55) | TLR7BTKERBB2LCKTEC | |
| SCHEMBL15156055 | 0.79 | SRC (0.55) | PIK3CDPIK3CAEGFRSRC | |
| SCHEMBL15145742 | 0.79 | SRC (0.55) | PIK3CDPIK3CAEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134685-A2 | NOVEL HYDRAZINO COMPOUNDS AS BTK INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |