Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.44 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.39 |
| ▸ | AMD1 | P17707 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803929 | 0.84 | ADORA3 (0.49) | TLR7EEF2KADORA2AADORA3ADORA2B | |
| SCHEMBL25269666 | 0.81 | MTOR (0.44) | TLR7AMD1 | |
| SCHEMBL19209529 | 0.80 | TLR7 (0.41) | TLR7EEF2KAMD1NSD2NSD3 | |
| SCHEMBL30558111 | 0.77 | TLR7 (0.41) | TLR7AMD1ADORA2AADORA3ADORA2B | |
| SCHEMBL23217008 | 0.76 | ALDH1A1 (0.43) | TLR7EEF2KAMD1NSD2NSD3 | |
| SCHEMBL20480733 | 0.76 | BTK (0.42) | TLR7EEF2K | |
| SCHEMBL16143478 | 0.76 | BTK (0.42) | TLR7EEF2K | |
| SCHEMBL28117979 | 0.75 | TLR7 (0.45) | TLR7AMD1NSD2NSD3TLR8 | |
| SCHEMBL29614483 | 0.75 | TLR7 (0.41) | TLR7NSD2NSD3ADORA2AADORA3 | |
| SCHEMBL15156546 | 0.74 | EGFR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165570-A1 | CYCLOALKYL OR HETEROCYCLYL SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2023-09-07 | — | — | WO | disclosed |