Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600624 | 0.80 | OPRK1 (0.42) | ALDH1A1PLAUOPRK1KDR | |
| SCHEMBL9927092 | 0.79 | SCN5A (0.36) | FFAR1 | |
| SCHEMBL26587451 | 0.79 | DGAT2 (0.35) | ALDH1A1OPRK1FFAR1 | |
| SCHEMBL28535766 | 0.79 | OPRK1 (0.48) | ALDH1A1OPRK1NPSR1 | |
| SCHEMBL983160 | 0.78 | PLAU (0.37) | ALDH1A1PLAUOPRK1KDR | |
| SCHEMBL427374 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1PLAUOPRK1 | |
| SCHEMBL28528521 | 0.78 | ALDH1A1 (0.40) | ALDH1A1PLAUOPRK1NPSR1 | |
| SCHEMBL22208305 | 0.77 | OPRK1 (0.38) | ALDH1A1OPRK1NPSR1 | |
| SCHEMBL4482054 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1PLAUOPRK1 | |
| Hydrochloric Acid SCHEMBL21457860 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1PLAUOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | disclosed |