SCHEMBL19209998

SCHEMBL19209998

CCCC(O)(CC(C)C)c1ccccc1N

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17374776 0.87 SMN1; SMN2 (0.33) GAASMN1; SMN2ALDH1A1
SCHEMBL631669 0.86 CNR1 (0.37) CNR1CNR2GAASMN1; SMN2CYP1A2
SCHEMBL3550577 0.79 CACNA1F (0.32) GAASMN1; SMN2
SCHEMBL7781942 0.76 HSP90AA1 (0.40) GAASMN1; SMN2CYP2C19ALDH1A1
SCHEMBL647668 0.75 HSP90AA1 (0.38) CNR1CNR2GAASMN1; SMN2CYP1A2
SCHEMBL2076194 0.75 ALDH1A1 (0.38) CNR1CNR2GAASMN1; SMN2CYP1A2
SCHEMBL13439637 0.73 CYP3A4 (0.41) CNR1CNR2GAACYP1A2CYP2C19
SCHEMBL13548757 0.72 AR (0.48) GAASMN1; SMN2ALDH1A1
SCHEMBL4802713 0.70 HSP90AA1 (0.42) SMN1; SMN2CYP2C19ALDH1A1
SCHEMBL3550576 0.70 SMN1; SMN2 (0.34) GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210198180-A1 PROCESS FOR PRODUCING SUBSTITUTED 4-AMINOINDANE DERIVATIVES FROM 2-(HYDROXYALKYL)-ANILINES BAYER AG (DE) 2021-07-01 US disclosed
US-20210198180-A1 PROCESS FOR PRODUCING SUBSTITUTED 4-AMINOINDANE DERIVATIVES FROM 2-(HYDROXYALKYL)-ANILINES BAYER AG (DE) 2021-07-01 US disclosed
CN-112088154-A Process for preparing substituted 4-aminoindan derivatives from 2- (hydroxyalkyl) -anilines 拜耳公司 2020-12-15 CN disclosed
US-20190039995-A1 METHOD FOR PREPARING SUBSTITUTED 4-AMINOINDANE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-07 US disclosed
US-20190039995-A1 METHOD FOR PREPARING SUBSTITUTED 4-AMINOINDANE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-07 US disclosed
EP-3411354-A1 METHOD FOR PRODUCING SUBSTITUTED 4-AMINOINDANE DERIVATIVES Bayer CropScience Aktiengesellschaft (DE) 2018-12-12 EP disclosed
WO-2017133981-A1 METHOD FOR PRODUCING SUBSTITUTED 4-AMINOINDANE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-10 WO disclosed
WO-2017133981-A1 METHOD FOR PRODUCING SUBSTITUTED 4-AMINOINDANE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198180-A1 PROCESS FOR PRODUCING SUBSTITUTED 4-AMINOINDANE DERIVATIVES FROM 2-(HYDROXYALKYL)-ANILINES HTR3C, HTR4, HRH4 CNR1 796/4885CNR2 280/4885GAA 3674/4885
US-20190039995-A1 METHOD FOR PREPARING SUBSTITUTED 4-AMINOINDANE DERIVATIVES NQO2, CCND2, CYP4F2 CNR1 885/4885CNR2 714/4885GAA 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.