Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | TPH1 | P17752 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733841 | 0.91 | LMNA (0.33) | S1PR1S1PR3S1PR5TPH1LMNA | |
| SCHEMBL13736704 | 0.88 | LMNA (0.35) | S1PR1S1PR3S1PR5TPH1LMNA | |
| SCHEMBL19210474 | 0.87 | RXRA (0.34) | FFAR1 | |
| SCHEMBL19210393 | 0.86 | MAPT (0.35) | LMNA | |
| SCHEMBL19210419 | 0.85 | CTSA (0.34) | S1PR1S1PR3S1PR5 | |
| SCHEMBL13734658 | 0.85 | PTPN1 (0.34) | S1PR3S1PR5FFAR1 | |
| SCHEMBL19210438 | 0.84 | IMPDH2 (0.33) | S1PR1S1PR3S1PR5 | |
| SCHEMBL19210396 | 0.84 | S1PR1 (0.35) | S1PR1TPH1LMNATSHRNFKB1 | |
| SCHEMBL19210449 | 0.83 | FFAR4 (0.36) | FFAR1 | |
| SCHEMBL19210489 | 0.81 | RXRA (0.39) | FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |