Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.40 |
| ▸ | ADH1A | P07327 | 3/20 | 0.40 |
| ▸ | ADH1C | P00326 | 2/20 | 0.40 |
| ▸ | ADH7 | P40394 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919882 | 0.84 | ADH1B (0.36) | ADH1BADH1AADH1C | |
| SCHEMBL131375 | 0.80 | ADH1B (0.43) | ADH1BADH1AADH1CADH7 | |
| SCHEMBL13497881 | 0.77 | ADH1B (0.40) | ADH1BADH1AADH1CADH7 | |
| SCHEMBL1919898 | 0.73 | ADH1B (0.36) | ADH1BADH1AADH1C | |
| SCHEMBL1920617 | 0.68 | ADH1B (0.32) | ADH1BADH1AADH1C | |
| SCHEMBL27616114 | 0.63 | ADH1B (0.46) | ADH1BADH1AADH1CADH7 | |
| SCHEMBL16350144 | 0.61 | ADH1B (0.39) | ADH1BADH1AADH1CADH7 | |
| SCHEMBL3853943 | 0.60 | — | — | |
| SCHEMBL2092508 | 0.60 | — | — | |
| SCHEMBL379255 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267632-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS INC (US) | 2017-09-21 | — | — | US | disclosed |
| US-20170267632-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS INC (US) | 2017-09-21 | — | — | US | disclosed |
| US-9695119-B2 | Methionine analogs and methods of using same | BIOXINESS PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170029369-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2017-02-02 | — | — | US | disclosed |
| US-20150329481-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150329481-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2015-11-19 | — | — | US | disclosed |
| US-20140142189-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-20140142189-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8580859-B2 | Methionine analogs and methods of using same | BIOXINESS PHARMACEUTICALS, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| EP-2326619-A2 | METHIONINE ANALOGS AND METHODS OF USING SAME | Bioxiness Pharmaceuticals, Inc. (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010014943-A2 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICS, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| WO-2010014943-A2 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICS, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267632-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | ADH1B 2175/4885ADH1A 3314/4885ADH1C 3572/4885 |
| US-20150329481-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | ADH1B 2175/4885ADH1A 3314/4885ADH1C 3572/4885 |
| US-20170029369-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | ADH1B 2175/4885ADH1A 3314/4885ADH1C 3572/4885 |
| US-20140142189-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | ADH1B 2175/4885ADH1A 3314/4885ADH1C 3572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.