Guanosine

Guanosine

SCHEMBL19211836

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=P(O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.68
▸ TGM2 P21980 1/20 0.68
▸ KRAS P01116 4/20 0.64
▸ HPGD P15428 1/20 0.63
▸ FUT5 Q11128 1/20 0.63
▸ HINT1 P49773 1/20 0.60
▸ P2RY2 P41231 2/20 0.59
▸ P2RY4 P51582 1/20 0.59
▸ P2RY6 Q15077 1/20 0.59
▸ P2RX3 P56373 1/20 0.58
▸ IMPDH2 P12268 5/20 0.57
▸ IMPDH1 P20839 1/20 0.57
▸ GSK3A P49840 2/20 0.57
▸ RPS6KA3 P51812 2/20 0.57
▸ MAPK14 Q16539 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanosine SCHEMBL30125158 1.00 NT5E (0.68) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL4625995 1.00 NT5E (0.68) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL30589987 0.99 NT5E (0.69) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL9827513 0.99 NT5E (0.69) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL6066347 0.99 NT5E (0.69) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL37404 0.96 NT5E (0.70) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL27797461 0.96 NT5E (0.70) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL4410882 0.95 TGM2 (0.65) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL22134208 0.95 NT5E (0.69) NT5ETGM2KRASHPGDFUT5
Guanosine SCHEMBL29046528 0.95 TGM2 (0.64) NT5ETGM2KRASHPGDFUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117480255-A Attenuated salmonella gallinarum strain and use thereof 全南大学校产学协力团 2024-01-30 — — CN claimed
CN-117427210-A Calcium phytate bone substitute and preparation method and application thereof 中国科学院化学研究所 2024-01-23 — — CN claimed
CN-114324540-B Guanosine tetraphosphoric acid electrochemical nano-enzyme sensor and preparation method thereof 天津商业大学 2023-12-26 — — CN claimed
CN-116555377-A Method for preparing guanosine tetraphosphoric acid by enzyme method 上海交通大学 2023-08-08 — — CN claimed
CN-117480255-A Attenuated salmonella gallinarum strain and use thereof 全南大学校产学协力团 2024-01-30 — — CN disclosed
CN-117480255-A Attenuated salmonella gallinarum strain and use thereof 全南大学校产学协力团 2024-01-30 — — CN disclosed
CN-117427210-A Calcium phytate bone substitute and preparation method and application thereof 中国科学院化学研究所 2024-01-23 — — CN disclosed
CN-114324540-B Guanosine tetraphosphoric acid electrochemical nano-enzyme sensor and preparation method thereof 天津商业大学 2023-12-26 — — CN disclosed
CN-114324540-B Guanosine tetraphosphoric acid electrochemical nano-enzyme sensor and preparation method thereof 天津商业大学 2023-12-26 — — CN disclosed
CN-114324540-B Guanosine tetraphosphoric acid electrochemical nano-enzyme sensor and preparation method thereof 天津商业大学 2023-12-26 — — CN disclosed
CN-116712555-A Drug-loaded bacterial outer membrane vesicle for targeted intervention in tumor nerve microenvironment and preparation method thereof 华中科技大学 2023-09-08 — — CN disclosed
CN-116555377-A Method for preparing guanosine tetraphosphoric acid by enzyme method 上海交通大学 2023-08-08 — — CN disclosed
CN-116555377-A Method for preparing guanosine tetraphosphoric acid by enzyme method 上海交通大学 2023-08-08 — — CN disclosed
EP-3414332-B1 IMPROVEMENT OF PHOTOSYNTHETIC ORGANISMS THROUGH THE MODULATION OF GUANOSINE TETRAPHOSPHATE HOMEOSTATIS CENTRE NAT RECH SCIENT (FR) 2022-06-29 — — EP disclosed
EP-3414332-B1 IMPROVEMENT OF PHOTOSYNTHETIC ORGANISMS THROUGH THE MODULATION OF GUANOSINE TETRAPHOSPHATE HOMEOSTATIS CENTRE NAT RECH SCIENT (FR) 2022-06-29 — — EP disclosed
US-20190169630-A1 IMPROVEMENT OF PHOTOSYNTHETIC ORGANISMS THROUGH THE MODULATION OF GUANOSINE TETRAPHOSPHATE HOMEOSTATIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS ) (FR) 2019-06-06 — — US disclosed
EP-3414332-A1 IMPROVEMENT OF PHOTOSYNTHETIC ORGANISMS THROUGH THE MODULATION OF GUANOSINE TETRAPHOSPHATE HOMEOSTATIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2018-12-19 — — EP disclosed
EP-3414332-A1 IMPROVEMENT OF PHOTOSYNTHETIC ORGANISMS THROUGH THE MODULATION OF GUANOSINE TETRAPHOSPHATE HOMEOSTATIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2018-12-19 — — EP disclosed
WO-2017137374-A1 IMPROVEMENT OF PHOTOSYNTHETIC ORGANISMS THROUGH THE MODULATION OF GUANOSINE TETRAPHOSPHATE HOMEOSTATIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) 2017-08-17 — — WO disclosed
WO-2017137374-A1 IMPROVEMENT OF PHOTOSYNTHETIC ORGANISMS THROUGH THE MODULATION OF GUANOSINE TETRAPHOSPHATE HOMEOSTATIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) 2017-08-17 — — WO disclosed
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