Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623359 | 0.90 | TSPO (0.46) | NR1H2NR1H3TSHRALDH1A1AOC3 | |
| SCHEMBL9809626 | 0.85 | MEN1 (0.48) | NR1H2NR1H3TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6982805 | 0.82 | NR1H2 (0.58) | NR1H2NR1H3TSHRALDH1A1AOC3 | |
| SCHEMBL2881081 | 0.80 | CYP2C19 (0.52) | NR1H2NR1H3TSHRALDH1A1AOC3 | |
| SCHEMBL7789996 | 0.80 | CHRNB2 (0.57) | ALDH1A1KDM4E | |
| SCHEMBL11881187 | 0.79 | NR1H2 (0.62) | NR1H2NR1H3TSHRALDH1A1AOC3 | |
| SCHEMBL642317 | 0.79 | CRHBP (0.61) | NR1H2NR1H3TSHRALDH1A1AOC3 | |
| SCHEMBL5604665 | 0.78 | TSPO (0.57) | NR1H2NR1H3TSHRALDH1A1AOC3 | |
| SCHEMBL10786006 | 0.78 | CRHBP (0.57) | NR1H2NR1H3TSHRALDH1A1CRHBP | |
| SCHEMBL12772106 | 0.78 | MEN1 (0.55) | NR1H2NR1H3ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | claimed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | claimed |
| EP-3414216-A1 | ARYLATION OF ALIPHATIC AMINES | AAA Chemistry ApS (DK) | 2018-12-19 | — | — | EP | claimed |
| WO-2017137047-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2017-08-17 | — | — | WO | claimed |
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| EP-3414216-A1 | ARYLATION OF ALIPHATIC AMINES | AAA Chemistry ApS (DK) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017137047-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2017-08-17 | — | — | WO | disclosed |
| WO-2017137047-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2017-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | NAT1, AHR, ABL1 | NR1H2 2404/4885NR1H3 1942/4885TSHR 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.