SCHEMBL7763499

SCHEMBL7763499

Cc1ccc(Nc2ccc(C)c(C)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
MEN1 O00255 1/20 0.63
G6PD P11413 1/20 0.63
KMT2A Q03164 1/20 0.63
HPGD P15428 2/20 0.56
RAPGEF4 Q8WZA2 1/20 0.56
MAPT P10636 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
APP P05067 1/20 0.48
ALDH1A1 P00352 2/20 0.47
ALOX15 P16050 2/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP3A4 P08684 1/20 0.47
THRB P10828 1/20 0.47
RECQL P46063 1/20 0.47
HIF1A Q16665 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921405 0.93 GAA (0.52) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL30508518 0.90 ALDH1A1 (0.53) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL31549984 0.90 ALDH1A1 (0.53) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL1155655 0.90 ALDH1A1 (0.53) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL1921952 0.86 ALDH1A1 (0.47) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL25994059 0.86 ALDH1A1 (0.47) GAAL3MBTL1MEN1G6PDKMT2A
Benzene SCHEMBL7148507 0.85 KMT2A (0.50) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL4826082 0.84 HPGD (0.60) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL30542248 0.84 HPGD (0.60) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL15385906 0.84 RAPGEF4 (0.52) GAAL3MBTL1MEN1G6PDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303325-B Efficient controllable preparation method of polyisoprene 中国科学院青岛生物能源与过程研究所 2022-07-05 CN disclosed
EP-3544984-B1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
EP-3712695-A1 ELECTROCHROMIC DEVICE, WEARABLE DEVICE, AND METHOD FOR DRIVING ELECTROCHROMIC DEVICE Ricoh Company, Ltd. (JP) 2020-09-23 EP disclosed
EP-3309851-B1 CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT NISSAN CHEMICAL CORP (JP) 2020-01-01 EP disclosed
WO-2016096069-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-06-23 WO disclosed
EP-0617005-B1 Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same FUJI XEROX CO LTD (JP) 2001-06-13 EP disclosed
US-5587263-A STABLE CHARGE TRANSPORT LAYER FUJI XEROX CO., LTD. (JP) 1996-12-24 US disclosed
US-5495049-A CHARGE TRANSFER COMPOUNDS FUJI XEROX CO., LTD. (JP) 1996-02-27 US disclosed
EP-0617005-A2 Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same FUJI XEROX CO., LTD. (JP) 1994-09-28 EP disclosed