SCHEMBL1921406

SCHEMBL1921406

Cc1ccc(Nc2ccccc2Nc2ccc(C)c(C)c2)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
RAB9A P51151 5/20 0.45
KMT2A Q03164 5/20 0.45
NPC1 O15118 4/20 0.45
LMNA P02545 2/20 0.45
MAPK13 O15264 1/20 0.45
MAPK12 P53778 1/20 0.45
MAPK11 Q15759 1/20 0.45
MAPK14 Q16539 1/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TP53 P04637 1/20 0.44
MEN1 O00255 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22814361 0.91 MAPK13 (0.50) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL6355590 0.86 MAPK14 (0.47) MAPTSMN1; SMN2HSD17B10KMT2ALMNA
SCHEMBL5492276 0.86 MAPT (0.65) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL6360440 0.86 KMT2A (0.48) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
Benzene SCHEMBL7148507 0.83 KMT2A (0.50) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL11219348 0.83 MAPT (0.60) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL30508518 0.83 ALDH1A1 (0.53) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL1155655 0.83 ALDH1A1 (0.53) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL31549984 0.83 ALDH1A1 (0.53) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL4826082 0.82 HPGD (0.60) MAPTSMN1; SMN2ALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed