SCHEMBL1921433

SCHEMBL1921433

c1ncnc(N2CCNCC2)n1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.63
ALDH1A1 P00352 2/20 0.63
HRH1 P35367 1/20 0.50
USP2 O75604 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TAAR1 Q96RJ0 1/20 0.47
CASP1 P29466 1/20 0.47
CASP4 P49662 1/20 0.47
CASP5 P51878 1/20 0.47
ADRB2 P07550 2/20 0.47
PLD1 Q13393 2/20 0.47
NCF1 P14598 1/20 0.47
CYP3A4 P08684 3/20 0.44
CYP2D6 P10635 2/20 0.44
TSHR P16473 2/20 0.44
ADRB1 P08588 2/20 0.43
MEN1 O00255 2/20 0.41
CYP1A2 P05177 2/20 0.41
KMT2A Q03164 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6791298 0.92 KDM4E (0.55) KDM4EALDH1A1HRH1USP2SMN1; SMN2
SCHEMBL9418619 0.83 SORD (0.50) KDM4EALDH1A1USP2SMN1; SMN2MEN1
SCHEMBL28710773 0.82 HRH1 (0.61) KDM4EALDH1A1HRH1USP2SMN1; SMN2
2-Piperazin-1-Yl-Pyrimidine SCHEMBL893739 0.79 ALDH1A1 (0.95) KDM4EALDH1A1HRH1USP2SMN1; SMN2
2-Piperazin-1-Yl-Pyrimidine SCHEMBL169214 0.79 ALDH1A1 (0.95) KDM4EALDH1A1HRH1USP2SMN1; SMN2
SCHEMBL3195427 0.78 SORD (0.43) KDM4EALDH1A1HRH1USP2SMN1; SMN2
SCHEMBL9803609 0.78 SORD (0.43) KDM4EALDH1A1HRH1USP2SMN1; SMN2
SCHEMBL9862128 0.78 SORD (0.46) KDM4EALDH1A1USP2TDP1TAAR1
2-Piperazin-1-Yl-Pyrimidine SCHEMBL5375472 0.77 ALDH1A1 (0.91) KDM4EALDH1A1HRH1USP2SMN1; SMN2
2-Piperazin-1-Yl-Pyrimidine SCHEMBL101561 0.77 ALDH1A1 (1.00) KDM4EALDH1A1HRH1USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574623-A Corrosion-resistant and wear-resistant coating for electromagnetic valve armature core of shock absorber and preparation method thereof 时硕科技(无锡)有限公司 2026-02-27 CN claimed
CN-113845725-B Flame-retardant polypropylene material with good water resistance and preparation method thereof 青岛塑科高分子科技有限公司 2023-03-21 CN claimed
CN-115073814-A Piperazine pyrophosphate intumescent flame retardant and preparation method thereof 青岛塑科高分子科技有限公司 2022-09-20 CN claimed
CN-115044001-A Method for producing water-soluble phenolic resin and co-producing aqueous calcium carbonate suspension by using white carbon black wastewater 安徽进化硅纳米材料科技有限公司 2022-09-13 CN claimed
CN-113845725-A Flame-retardant polypropylene material with good water resistance and preparation method thereof 青岛塑科高分子科技有限公司 2021-12-28 CN claimed
CN-107459645-A Carbon forming agent based on three piperazine triazines and preparation method thereof 金湖金凌新材料科技有限公司 2017-12-12 CN claimed
CN-104263175-B A kind of nano modification anticorrosive coating JURONG YIGE NANO MATERIAL FACTORY (CN) 2017-01-04 CN claimed
CN-104263175-A Nano modified anticorrosive coating material JURONG YIGE NANO MATERIALS FACTORY 2015-01-07 CN claimed
CN-104194545-A Nanometer modified anti-contamination external wall coating JURONG YIGE NANO MATERIALS FACTORY 2014-12-10 CN claimed
CN-103127135-A Triterpene derivative and preparation method and application UNIV BEIJING 2013-06-05 CN claimed
EP-0441134-A2 Flame retardant polymeric compositions HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-14 EP claimed
EP-0101735-B1 SUBSTITUTED OXO-PIPERAZINYL-TRIAZINES AND UV LIGHT STABILIZED COMPOSITIONS The B.F. GOODRICH Company (US) 1986-10-29 EP claimed
JP-4218542-A None JP disclosed
CN-121574623-A Corrosion-resistant and wear-resistant coating for electromagnetic valve armature core of shock absorber and preparation method thereof 时硕科技(无锡)有限公司 2026-02-27 CN disclosed
CN-121574623-A Corrosion-resistant and wear-resistant coating for electromagnetic valve armature core of shock absorber and preparation method thereof 时硕科技(无锡)有限公司 2026-02-27 CN disclosed
EP-3728234-B1 RADIOLABELED COMPOUNDS HOFFMANN LA ROCHE (CH) 2025-05-14 EP disclosed
EP-0441134-A2 Flame retardant polymeric compositions HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-14 EP disclosed
EP-0441134-A2 Flame retardant polymeric compositions HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-14 EP disclosed
WO-1991006542-A1 PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES THE UPJOHN COMPANY (US) 1991-05-16 WO disclosed
EP-0021678-A1 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof Takeda Chemical Industries, Ltd. (JP) 1981-01-07 EP disclosed