SCHEMBL1921484

SCHEMBL1921484

FC(F)(F)c1cccc(Nc2ccccc2Nc2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.77
ALDH1A1 P00352 2/20 0.77
GAA P10253 2/20 0.77
RAB9A P51151 2/20 0.77
SMN1; SMN2 Q16637 1/20 0.77
RXFP1 Q9HBX9 2/20 0.65
IDH2 P48735 2/20 0.64
YAP1 P46937 1/20 0.61
TEAD4 Q15561 1/20 0.61
TEAD2 Q15562 1/20 0.61
RAPGEF4 Q8WZA2 1/20 0.57
KIF11 P52732 1/20 0.57
AKR1C3 P42330 1/20 0.56
AKR1C2 P52895 1/20 0.56
MPO P05164 2/20 0.55
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
HTT P42858 1/20 0.54
KDM4E B2RXH2 1/20 0.54
GFER P55789 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20693799 0.89 ALDH1A1 (0.69) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL11566545 0.89 ALDH1A1 (0.68) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL4064881 0.88 MAPT (1.00) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL10215929 0.88 GAA (0.67) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL20551660 0.88 GAA (0.67) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL29414647 0.88 MAPT (1.00) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL18120683 0.88 MAPT (0.67) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL394991 0.87 KIF11 (0.70) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL30575363 0.86 IDH2 (0.77) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL7347670 0.86 IDH2 (0.77) MAPTALDH1A1GAARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed