Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | IDH2 | P48735 | 2/20 | 0.56 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.55 |
| ▸ | TEAD2 | Q15562 | 2/20 | 0.55 |
| ▸ | YAP1 | P46937 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 3/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 3/20 | 0.52 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.51 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921484 | 0.89 | MAPT (0.77) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL394991 | 0.84 | KIF11 (0.70) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20693799 | 0.82 | ALDH1A1 (0.69) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29414647 | 0.81 | MAPT (1.00) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20551660 | 0.81 | GAA (0.67) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18120683 | 0.81 | MAPT (0.67) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10215929 | 0.81 | GAA (0.67) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4064881 | 0.81 | MAPT (1.00) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1921482 | 0.80 | KIF11 (0.70) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30671654 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002269-A1 | Composition and use of this composition as a stabilizer in lubricating oils, and product obtained | The B.F. GOODRICH Company (US) | 1979-06-13 | — | — | EP | disclosed |