Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.43 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24429673 | 0.88 | KAT6A (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25918378 | 0.86 | GPR119 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1817484 | 0.78 | TRPV4 (0.47) | KAT6AMAPTKMT2ATRPV4L3MBTL1 | |
| SCHEMBL30540030 | 0.78 | TRPV4 (0.47) | KAT6AMAPTKMT2ATRPV4L3MBTL1 | |
| SCHEMBL4493224 | 0.76 | TRPV4 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2212307 | 0.76 | LTA4H (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29651893 | 0.75 | CA1 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17433278 | 0.75 | GPR84 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19059333 | 0.75 | CA12 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17432926 | 0.74 | MRGPRX4 (0.47) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725442-B2 | Heterocyclic derivative having PGD2 receptor antagonist activity | SHIONOGI & CO., LTD. (JP) | 2017-08-08 | — | — | US | disclosed |