Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357488 | 0.69 | ACHE (0.43) | PTGS2CYP3A4ACHEBACE1ALOX5 | |
| SCHEMBL4659945 | 0.68 | GPR84 (0.41) | HTTTP53MAPTTSHRGAA | |
| SCHEMBL6898154 | 0.68 | ACHE (0.46) | PTGS2ACHEBACE1ALOX5GPR84 | |
| SCHEMBL6903485 | 0.68 | ACHE (0.46) | PTGS2ACHEBACE1ALOX5GPR84 | |
| SCHEMBL27482175 | 0.68 | ACHE (0.46) | PTGS2ACHEBACE1ALOX5GPR84 | |
| SCHEMBL6896832 | 0.68 | ACHE (0.46) | PTGS2ACHEBACE1ALOX5GPR84 | |
| SCHEMBL11543697 | 0.68 | ACHE (0.46) | PTGS2ACHEBACE1ALOX5GPR84 | |
| SCHEMBL243893 | 0.68 | ACHE (0.46) | PTGS2ACHEBACE1ALOX5GPR84 | |
| SCHEMBL6901931 | 0.68 | ACHE (0.46) | PTGS2ACHEBACE1ALOX5GPR84 | |
| SCHEMBL1235894 | 0.67 | GSTP1 (0.43) | PTGS2ACHEBACE1ALOX5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2446026-B1 | TRANSAMINASE REACTIONS | CODEXIS INC (US) | 2017-08-09 | — | — | EP | disclosed |