Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 6/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 6/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 6/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921845 | 0.91 | ELANE (0.34) | ACACBACACAELANESLC5A1CA2 | |
| SCHEMBL1920882 | 0.85 | ELANE (0.37) | ELANECHEK1AURKACSNK1A1CDK8 | |
| SCHEMBL1921407 | 0.84 | KCNJ6 (0.39) | KCNJ6KCNJ5KCNJ3ACACBACACA | |
| SCHEMBL1921322 | 0.80 | ALDH1A1 (0.39) | KCNJ6KCNJ5KCNJ3CHEK1AURKA | |
| SCHEMBL1921690 | 0.80 | ELANE (0.34) | ELANECHEK1AURKACSNK1A1CDK8 | |
| SCHEMBL1923158 | 0.77 | CHEK1 (0.47) | KCNJ6KCNJ5KCNJ3CHEK1AURKA | |
| SCHEMBL1921349 | 0.73 | CHEK1 (0.45) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL12533937 | 0.71 | NPC1 (0.44) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL1921732 | 0.68 | CSNK2A2 (0.39) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL1920560 | 0.68 | TLR7 (0.42) | CHEK1AURKACSNK1A1CDK8NEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170833-B1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI AVENTIS (FR) | 2011-06-01 | — | — | EP | claimed |