Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 5/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920882 | 0.94 | ELANE (0.37) | ELANESLC5A1MAPK13MAPK12MAPK11 | |
| SCHEMBL1921845 | 0.83 | ELANE (0.34) | ELANESLC5A1MAPK13MAPK14CA2 | |
| SCHEMBL1921659 | 0.80 | KCNJ6 (0.36) | ELANESLC5A1CA2KHKCHEK1 | |
| SCHEMBL1920962 | 0.77 | CHEK1 (0.43) | KHKCHEK1AURKACSNK1A1CDK8 | |
| SCHEMBL1921521 | 0.74 | ALDH1A1 (0.44) | PLA2G2A | |
| SCHEMBL1922920 | 0.72 | MPO (0.42) | ELANEKHK | |
| SCHEMBL1921731 | 0.71 | PLA2G2A (0.40) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL8990079 | 0.70 | ELANE (0.58) | ELANECA2PLA2G2A | |
| SCHEMBL1921320 | 0.66 | ALDH1A1 (0.54) | — | |
| SCHEMBL13984750 | 0.66 | CDK8 (0.38) | KHKCHEK1AURKACSNK1A1CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170833-B1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI AVENTIS (FR) | 2011-06-01 | — | — | EP | claimed |