Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.30 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921659 | 0.91 | KCNJ6 (0.36) | ELANECA2ACACBACACASLC5A1 | |
| SCHEMBL1921121 | 0.84 | TLR8 (0.36) | ACACBACACAMAPK14MAPK13SLC2A1 | |
| SCHEMBL1921690 | 0.83 | ELANE (0.34) | ELANECA2SLC5A1MAPK14MAPK13 | |
| SCHEMBL1920882 | 0.76 | ELANE (0.37) | ELANECA2SLC5A1MAPK14MAPK13 | |
| SCHEMBL1921407 | 0.75 | KCNJ6 (0.39) | ACACBACACA | |
| SCHEMBL1921322 | 0.72 | ALDH1A1 (0.39) | MAPK14MAPK13 | |
| SCHEMBL1923158 | 0.67 | CHEK1 (0.47) | — | |
| SCHEMBL1922389 | 0.67 | ABCG2 (0.41) | MAPK14MAPK13 | |
| SCHEMBL1921349 | 0.63 | CHEK1 (0.45) | — | |
| SCHEMBL12533937 | 0.62 | NPC1 (0.44) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170833-B1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI AVENTIS (FR) | 2011-06-01 | — | — | EP | claimed |