SCHEMBL1921734

SCHEMBL1921734

CCCn1c2ccc(I)cc2c2cc(I)ccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.51
MAPT P10636 3/20 0.51
KDM4E B2RXH2 3/20 0.51
HTT P42858 3/20 0.51
LMNA P02545 2/20 0.51
GFER P55789 1/20 0.51
ALDH1A1 P00352 3/20 0.47
CNR2 P34972 3/20 0.40
NPC1 O15118 1/20 0.40
DNMT1 P26358 1/20 0.39
RORC P51449 4/20 0.38
PGR P06401 3/20 0.38
RORA P35398 3/20 0.38
RORB Q92753 3/20 0.38
PSEN1 P49768 1/20 0.37
PSEN2 P49810 1/20 0.37
APH1B Q8WW43 1/20 0.37
NCSTN Q92542 1/20 0.37
APH1A Q96BI3 1/20 0.37
PSENEN Q9NZ42 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921258 0.91 HPGD (0.60) HPGDMAPTKDM4EHTTLMNA
SCHEMBL1921908 0.89 RORA (0.48) HPGDMAPTKDM4EHTTLMNA
SCHEMBL14893382 0.85 PSEN1 (0.52) CNR2NPC1RORCPGRRORA
SCHEMBL8143866 0.85 PSEN1 (0.52) CNR2NPC1RORCPGRRORA
SCHEMBL2957510 0.85 PSEN1 (0.52) CNR2NPC1RORCPGRRORA
SCHEMBL4353679 0.85 PSEN1 (0.52) CNR2NPC1RORCPGRRORA
SCHEMBL1921140 0.83 KDM4E (0.50) HPGDMAPTKDM4EHTTLMNA
SCHEMBL1921229 0.81 RORA (0.56) HPGDALDH1A1CNR2NPC1RORC
SCHEMBL14908435 0.79 CNR2 (0.59) CNR2RORCPGRRORARORB
SCHEMBL27641643 0.79 CNR2 (0.59) CNR2RORCPGRRORARORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed