SCHEMBL1921229

SCHEMBL1921229

CCCCn1c2ccccc2c2cc(I)ccc21

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RORA P35398 6/20 0.56
RORC P51449 6/20 0.56
RORB Q92753 6/20 0.56
PGR P06401 5/20 0.56
CNR2 P34972 10/20 0.54
ALDH1A1 P00352 2/20 0.51
NPC1 O15118 1/20 0.50
HPGD P15428 1/20 0.50
CNR1 P21554 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14908435 0.94 CNR2 (0.59) RORARORCRORBPGRCNR2
SCHEMBL27641643 0.94 CNR2 (0.59) RORARORCRORBPGRCNR2
SCHEMBL1921908 0.92 RORA (0.48) RORARORCRORBPGRCNR2
SCHEMBL1921258 0.90 HPGD (0.60) RORARORCRORBPGRCNR2
SCHEMBL4804298 0.89 MAOA (0.53) CNR2
SCHEMBL4802610 0.89 MAOA (0.53) CNR2
SCHEMBL16099549 0.86 FABP4 (0.45) CNR2ALDH1A1HPGD
SCHEMBL14893382 0.85 PSEN1 (0.52) RORARORCRORBPGRCNR2
SCHEMBL8143866 0.85 PSEN1 (0.52) RORARORCRORBPGRCNR2
SCHEMBL4353679 0.85 PSEN1 (0.52) RORARORCRORBPGRCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2327739-B1 Novel triarylamine polymer, process for its production and its use TOSOH CORP (JP) 2014-05-07 EP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed