SCHEMBL1921908

SCHEMBL1921908

CCCCn1c2ccc(I)cc2c2cc(I)ccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 6/20 0.48
RORC P51449 6/20 0.48
RORB Q92753 6/20 0.48
PGR P06401 5/20 0.48
PSEN1 P49768 1/20 0.44
PSEN2 P49810 1/20 0.44
APH1B Q8WW43 1/20 0.44
NCSTN Q92542 1/20 0.44
APH1A Q96BI3 1/20 0.44
PSENEN Q9NZ42 1/20 0.44
CNR2 P34972 5/20 0.43
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 1/20 0.43
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
GFER P55789 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4353679 0.93 PSEN1 (0.52) RORARORCRORBPGRPSEN1
SCHEMBL14893382 0.93 PSEN1 (0.52) RORARORCRORBPGRPSEN1
SCHEMBL2957510 0.93 PSEN1 (0.52) RORARORCRORBPGRPSEN1
SCHEMBL8143866 0.93 PSEN1 (0.52) RORARORCRORBPGRPSEN1
SCHEMBL1921229 0.92 RORA (0.56) RORARORCRORBPGRCNR2
SCHEMBL1921734 0.89 HPGD (0.51) RORARORCRORBPGRPSEN1
SCHEMBL14908435 0.86 CNR2 (0.59) RORARORCRORBPGRPSEN1
SCHEMBL27641643 0.86 CNR2 (0.59) RORARORCRORBPGRPSEN1
SCHEMBL18261951 0.85 KDM4E (0.47) RORARORCRORBPSEN1PSEN2
SCHEMBL18261947 0.85 KDM4E (0.47) RORARORCRORBPSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103739593-A Perylene monoimide dimers and preparation method thereof UNIV DALIAN TECH 2014-04-23 CN disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed