Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.52 |
| ▸ | CNR2 | P34972 | 9/20 | 0.48 |
| ▸ | RORA | P35398 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | RORB | Q92753 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14893382 | 1.00 | PSEN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2957510 | 1.00 | PSEN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8143866 | 1.00 | PSEN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1921908 | 0.93 | RORA (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14908435 | 0.92 | CNR2 (0.59) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27641643 | 0.92 | CNR2 (0.59) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18261947 | 0.91 | KDM4E (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18261951 | 0.91 | KDM4E (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14893345 | 0.87 | PTGER4 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6859976 | 0.86 | PSEN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104151533-B | A kind of fluorescent conjugated polymer containing phenothiazine group and synthetic method thereof and application | 华南理工大学 | 2016-10-05 | — | — | CN | disclosed |
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | NATIONAL SCIENCE FOUNDATION | 2015-10-01 | — | — | US | disclosed |
| US-8993804-B2 | Highly active multidentate catalysts for efficient alkyne metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-03-31 | — | — | US | disclosed |
| US-20130261295-A1 | Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-10-03 | — | — | US | disclosed |
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | PCNA, TRIM58, CAD | PSEN1 4496/4885PSEN2 4541/4885APH1B 3027/4885 |
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | C5, CCNE1, QSOX1 | PSEN1 3557/4885PSEN2 3722/4885APH1B 1677/4885 |
| US-20130261295-A1 | Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis | PCNA, TRIM58, CAD | PSEN1 4496/4885PSEN2 4541/4885APH1B 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.