SCHEMBL1921824

SCHEMBL1921824

CCCn1c2ccc(Cl)cc2c2cc(Cl)ccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSEN1 P49768 4/20 0.57
▸ PSEN2 P49810 4/20 0.57
▸ APH1B Q8WW43 4/20 0.57
▸ NCSTN Q92542 4/20 0.57
▸ APH1A Q96BI3 4/20 0.57
▸ PSENEN Q9NZ42 4/20 0.57
▸ PTGER4 P35408 1/20 0.54
▸ HPGD P15428 2/20 0.51
▸ MAPT P10636 2/20 0.51
▸ HTT P42858 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ GFER P55789 1/20 0.51
▸ HTR6 P50406 1/20 0.50
▸ PLK1 P53350 1/20 0.48
▸ RAB9A P51151 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921889 0.91 ALDH1A1 (0.60) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1921483 0.89 PSEN1 (0.67) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL16120103 0.84 HPGD (0.57) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1921261 0.83 PTGER4 (0.72) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL551120 0.83 PSEN1 (0.77) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29660662 0.82 ALDH1A1 (0.54) HPGDMAPTPLK1ALDH1A1TP53
SCHEMBL20291531 0.82 ALDH1A1 (0.54) HPGDMAPTPLK1ALDH1A1TP53
SCHEMBL1923371 0.81 PSEN1 (0.63) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13304767 0.78 RORA (0.55) HPGDMAPTHTTKDM4ELMNA
SCHEMBL18655576 0.77 MAPT (0.57) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 — — EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 — — EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 — — US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 — — US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 — — US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 — — EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 — — US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 — — US disclosed
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