Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HBB | P68871 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921288 | 1.00 | MAPT (0.65) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL27825721 | 0.91 | MAPT (0.67) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL1921261 | 0.91 | PTGER4 (0.72) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL2108365 | 0.89 | MAPT (0.55) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL14037008 | 0.89 | MAPT (0.57) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL8086738 | 0.87 | ALDH1A1 (0.72) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL1921889 | 0.86 | ALDH1A1 (0.60) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL1923371 | 0.83 | PSEN1 (0.63) | MAPTKDM4EALDH1A1L3MBTL1TSHR | |
| Chlorobenzene SCHEMBL28571942 | 0.83 | ALDH1A1 (0.60) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL13979310 | 0.83 | KDM4E (0.70) | MAPTTP53KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |