SCHEMBL19219009

SCHEMBL19219009

COc1cc(C=O)cc(OC)c1OC(=O)COCC(=O)Oc1c(OC)cc(C=O)cc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.52
MAPK1 P28482 1/20 0.52
HPGD P15428 2/20 0.45
GAA P10253 1/20 0.45
HTT P42858 1/20 0.45
KDM4E B2RXH2 1/20 0.45
HTR1A P08908 1/20 0.45
HTR2C P28335 1/20 0.45
HSD17B10 Q99714 1/20 0.45
POLB P06746 1/20 0.45
TRIM24 O15164 1/20 0.44
ALDH5A1 P51649 1/20 0.44
ABAT P80404 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9329178 0.85 ALDH1A1 (0.50) ALDH1A1MAPK1HPGDGAAHTT
SCHEMBL19214422 0.84 ALDH1A1 (0.40) ALDH1A1MAPK1KDM4EPOLBKMT2A
SCHEMBL8038069 0.83 ALDH1A1 (0.48) ALDH1A1MAPK1HPGDGAAHTT
SCHEMBL3395431 0.80 TUBB4A (0.62) ALDH1A1MAPK1HPGDGAAHTT
SCHEMBL96635 0.78 ALDH1A1 (0.59) ALDH1A1MAPK1HPGDGAAHTT
SCHEMBL16619850 0.78 ALDH1A1 (0.59) ALDH1A1MAPK1HPGDGAAHTT
SCHEMBL13179877 0.78 ALDH1A1 (0.50) ALDH1A1MAPK1HPGDGAAHTT
SCHEMBL13144674 0.78 ALDH1A1 (0.49) ALDH1A1MAPK1HPGDGAAHTT
Ethane SCHEMBL8038073 0.78 TUBB4A (0.60) ALDH1A1MAPK1HPGDGAAHTT
SCHEMBL8356454 0.78 TOP2A (0.56) ALDH1A1MAPK1HTR1AHTR2CKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 ALDH1A1 3809/4885MAPK1 1871/4885HPGD 2580/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 ALDH1A1 4014/4885MAPK1 2090/4885HPGD 2788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.