Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL530570 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL2352340 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL8518463 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL5384786 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL4953759 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL8601641 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL1925892 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL433597 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL717375 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 | |
| Acetic Acid SCHEMBL534555 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105602552-B | Fluorescent organic light-emitting material and organic electroluminescent device | 友达光电股份有限公司 | 2018-09-07 | — | — | CN | disclosed |
| US-20170170419-A1 | ORGANIC FLUORESCENT LUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE | AU OPTRONICS CORPORATION (TW) | 2017-06-15 | — | — | US | disclosed |
| US-9647294-B2 | Non-aqueous electrolytic solution, electrochemical element using same, and alkynyl compound used therefor | UBE INDUSTRIES, LTD. (JP) | 2017-05-09 | — | — | US | disclosed |
| EP-2533344-B1 | NON-AQUEOUS ELECTROLYTIC SOLUTION, ELECTROCHEMICAL ELEMENT USING THE SAME, AND ALKYNYL COMPOUND USED THEREFOR | UBE INDUSTRIES (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2883867-A2 | Non-aqueous electrolytic solution, electrochemical element using the same and alkynyl compound used therefor | Ube Industries, Ltd. (JP) | 2015-06-17 | — | — | EP | disclosed |
| US-8658735-B2 | Polymerizable monomer, graft copolymer, and surface modifier | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8450352-B2 | Thiazole compounds and their use for inhibiting phosphodiesterase 4, TNF-α, and IL-4 | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-2533344-A1 | NON-AQUEOUS ELECTROLYTIC SOLUTION, ELECTROCHEMICAL ELEMENT USING SAME, AND ALKYNYL COMPOUND USED THEREFOR | Ube Industries, Ltd. (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-20120301797-A1 | NON-AQUEOUS ELECTROLYTIC SOLUTION, ELECTROCHEMICAL ELEMENT USING SAME, AND ALKYNYL COMPOUND USED THEREFOR | UBE INDUSTRIES, LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| US-20110269905-A1 | Polymerizable Monomer, Graft Copolymer, and Surface Modifier | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2011-11-03 | — | — | US | disclosed |
| EP-2330138-A1 | POLYMERIZABLE MONOMER, GRAFT COPOLYMER, AND SURFACE MODIFIER | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2011-06-08 | — | — | EP | disclosed |
| US-20100094002-A1 | Thiazole Compound and Use Thereof | OTSUKA PHARMACEUTICAL CO., LTD. | 2010-04-15 | — | — | US | disclosed |
| US-7655680-B2 | (E)-3-[2-(3,4-diethoxyphenyl)thiazole-4-yl]-1-(2-methoxyphenyl)propenone; inhibiting the activity of phosphodiesterase 4, the production of tumor necrosis factor alpha, and the production of interleukin 4; atopic dermatitis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-02-02 | — | — | US | disclosed |
| US-20080039511-A1 | Thiazole Compound and Use Thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1748044-A1 | THIAZOLE COMPOUND AND USE THEREOF | Otsuka Pharmaceutical Company, Limited (JP) | 2007-01-31 | — | — | EP | disclosed |
| EP-0232776-B1 | 2,5,6,7-TETRANOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1990-10-24 | — | — | EP | disclosed |
| US-4822804-A | 5,6,7,-trinor-4,8-inter-m-phenylene 2-nor PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0232776-A2 | 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1987-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170170419-A1 | ORGANIC FLUORESCENT LUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE | AOX1, EML4, IK | ESR1 101/4885MEN1 2731/4885KMT2A 2875/4885 |
| US-20110269905-A1 | Polymerizable Monomer, Graft Copolymer, and Surface Modifier | ITGA1, CHRM1, C3AR1 | ESR1 1445/4885MEN1 3002/4885KMT2A 2599/4885 |
| US-20100094002-A1 | Thiazole Compound and Use Thereof | PDE3B, IL4, PDE4A | ESR1 2894/4885MEN1 1975/4885KMT2A 4633/4885 |
| US-20080039511-A1 | Thiazole Compound and Use Thereof | PDE3B, PDE3A, PDE4A | ESR1 4166/4885MEN1 2252/4885KMT2A 3873/4885 |
| US-20120301797-A1 | NON-AQUEOUS ELECTROLYTIC SOLUTION, ELECTROCHEMICAL ELEMENT USING SAME, AND ALKYNYL COMPOUND USED THEREFOR | WEE2, WEE1, NOTUM | ESR1 377/4885MEN1 2673/4885KMT2A 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.