Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723487 | 0.83 | TSHR (0.38) | LMNA | |
| SCHEMBL18433800 | 0.83 | LMNA (0.32) | LMNA | |
| SCHEMBL14793409 | 0.79 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL3297051 | 0.77 | IDO1 (0.41) | LMNACYP4F2CYP4A11EPHX1 | |
| SCHEMBL19220499 | 0.76 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL19219785 | 0.74 | ALDH1A1 (0.40) | LMNAEPHX1 | |
| SCHEMBL19194465 | 0.73 | CYP4F2 (0.31) | CYP4F2CYP4A11 | |
| SCHEMBL18387130 | 0.70 | LMNA (0.37) | LMNA | |
| SCHEMBL18731843 | 0.69 | LMNA (0.35) | LMNA | |
| SCHEMBL30515527 | 0.68 | IDO1 (0.34) | LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902716-B2 | Fluorinated benzofuranyl-pyrimidine derivatives containing a sulfone group | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-27 | — | — | US | disclosed |
| US-20170226092-A1 | FLUORINATED BENZOFURANYL-PYRIMIDINE DERIVATIVES CONTAINING A SUFLONE GROUP | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226092-A1 | FLUORINATED BENZOFURANYL-PYRIMIDINE DERIVATIVES CONTAINING A SUFLONE GROUP | FANCF, FLI1, FANCD2 | LMNA 626/4885CYP4F2 132/4885CYP4A11 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.