Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19824586 | 0.80 | FDFT1 (0.53) | MMP2MMEFDFT1 | |
| SCHEMBL17195125 | 0.80 | RARB (0.45) | MMP2MMP3FDFT1 | |
| SCHEMBL9670504 | 0.79 | CA2 (0.37) | ALDH1A1CYP3A4PPARGPPARAFDFT1 | |
| SCHEMBL11807655 | 0.79 | GRIA4 (0.51) | ALDH1A1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL19226784 | 0.78 | MMP2 (0.37) | ALDH1A1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL30920080 | 0.78 | MAOB (0.51) | ALDH1A1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL21235252 | 0.78 | MAOB (0.51) | ALDH1A1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL18559001 | 0.78 | TDP1 (0.52) | ALDH1A1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL19258910 | 0.78 | TDP1 (0.46) | SMN1; SMN2PPARGPPARAMAOB | |
| SCHEMBL11803867 | 0.78 | GRIA4 (0.50) | ALDH1A1MAPTMEN1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9726933-B2 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |