SCHEMBL19227199

SCHEMBL19227199

CCCCCCCCCCCCCCCCCCCC(COC(=O)CC)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.58
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
PRKCA P17252 3/20 0.45
PRKCE Q02156 1/20 0.45
PRKCQ Q04759 1/20 0.45
PRKCD Q05655 1/20 0.45
LPAR1 Q92633 2/20 0.44
LPAR3 Q9UBY5 2/20 0.44
DNM1 Q05193 1/20 0.43
TLR2 O60603 2/20 0.43
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26045881 0.87 LPAR1 (0.59) NAAAALDH1A1LMNAPRKCAPRKCE
SCHEMBL11297774 0.87 LPAR1 (0.46) NAAAALDH1A1LMNALPAR1LPAR3
SCHEMBL2195313 0.85 LPAR1 (0.56) NAAAALDH1A1LMNAPRKCAPRKCE
SCHEMBL11297776 0.85 LPAR1 (0.45) NAAAALDH1A1LMNALPAR1LPAR3
SCHEMBL18699114 0.84 DNM1 (0.47) NAAAALDH1A1LMNALPAR1LPAR3
SCHEMBL19227188 0.84 DNM1 (0.47) NAAAALDH1A1LMNALPAR1LPAR3
SCHEMBL18041137 0.83 ALDH1A1 (0.60) NAAAALDH1A1LMNAPRKCAPRKCE
SCHEMBL27793214 0.83 LMNA (0.64) ALDH1A1LMNAPRKCAPRKCEPRKCQ
Ammonia Solution, Strong SCHEMBL6303935 0.82 NAAA (0.59) NAAAALDH1A1LMNADNM1MAPT
SCHEMBL446039 0.81 NAAA (0.48) NAAAALDH1A1LMNAPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3202760-A1 PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY Alnylam Pharmaceuticals, Inc. (US) 2017-08-09 EP disclosed