Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 13/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | FXR2 | P51116 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230369 | 0.92 | ITGB3 (0.36) | ITGB3ITGA2BNR1H4NPC1RAB9A | |
| SCHEMBL19230576 | 0.89 | ITGB3 (0.35) | ITGB3ITGA2B | |
| SCHEMBL19230512 | 0.84 | NR1H4 (0.37) | ITGB3ITGA2BNR1H4MRGPRX4FXR2 | |
| SCHEMBL19230827 | 0.77 | NR1H4 (0.37) | ITGB3ITGA2BNR1H4 | |
| SCHEMBL19620251 | 0.76 | NR1H4 (0.40) | NR1H4MRGPRX4FXR2 | |
| SCHEMBL19230696 | 0.76 | ITGB3 (0.39) | ITGB3ITGA2BNR1H4 | |
| SCHEMBL19230320 | 0.76 | FAAH (0.38) | ITGB3ITGA2B | |
| SCHEMBL19230560 | 0.76 | NR1H4 (0.37) | ITGB3ITGA2BNR1H4MRGPRX4 | |
| SCHEMBL19230633 | 0.76 | MRGPRX4 (0.38) | ITGB3ITGA2BNR1H4MRGPRX4 | |
| SCHEMBL20094741 | 0.75 | OPRD1 (0.35) | NR1H4MRGPRX4NPC1NR4A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |